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- DLL4 is a new Biomarker of Cardiometabolic disorders.
- High Affinity Receptor: rh NOTCH1 Fc or NOTCH1 His Tag (HEK293).
- Tracer: rh DLL4 (HEK293) Biotinylated or rh DLL4 Fc (HEK293)
- Calibration: rh rh DLL4 His Tag (HEK293)
- Luminescence Read on Top
- Size: 4 x 96 T
Research References:
- Fujimaki S, Matsumoto T, Muramatsu M, Nagahisa H, Horii N, Seko D, Masuda S, Wang X, Asakura Y, Takahashi Y, Miyamoto Y, Usuki S, Yasunaga KI, Kamei Y, Nishinakamura R, Minami T, Fukuda T, Asakura A, Ono Y. The endothelial Dll4-muscular Notch2 axis regulates skeletal muscle mass. Nat Metab. 2022 Feb;4(2):180-189. PMID: 35228746.
- Alex Aupetit , et al. Endothelial DLL4 Is an Adipose Depot-Specific Fasting Sensor Regulating Fatty Acid Fluxes. Arterioscler Thromb Vasc Biol. 2023 May;43(5):684-696
- Yang S, et al. KLF13 restrains Dll4-muscular Notch2 axis to improve the muscle atrophy. J Cachexia Sarcopenia Muscle. 2024 Jul 8. Epub ahead of print. PMID: 38973459
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