Description
Yang L, et al. GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand. Nat Med. 2017 Aug 28. doi: 10.1038/nm.4394.
Growth differentiation factor 15 (GDF15; also known as MIC-1) is a divergent member of the TGF-β superfamily and is associated with body-weight regulation in humans and rodents.
Growth Differentiation Factor-15 is a reliable biomarker for heart failure.
Citations:
Nandini Nair, and Enrique Gongora "Correlations of GDF-15 with sST2, MMPs, and worsening functional capacity in idiopathic dilated cardiomyopathy: Can we gain new insights into the pathophysiology?" J Circ Biomark. 2018 Jan 19;7:1849454417751735. doi: 10.1177/1849454417751735
Features
Size: 2 x 96 T
Standard Range: 6.25-400 pg/ml
Dynamic Range: 6.25-400pg/ml
Sensitivity: 3 pg/ml
Sample Type: serum, EDTA plasma
Sample Requires: 125 uL
Dilution Factor: 2~ 4
Intra-CV: 2-4%
Inter-CV: 4-8%
Protocol: PDF