Pro NGF (Human) ELISA Kit
Product Code: SK00307-06
Our Price: $690.00
Description
- ProNGF, the precursor of mature nerve growth factor (NGF), is the most abundant form of NGF in the brain. ProNGF and mature NGF differ significantly in their receptor interaction properties and in their bioactivity. ProNGF increases markedly in the cortex of Alzheimer's disease (AD) brains and proNGF\NGF imbalance has been postulated to play a role in neurodegeneration. (Tiveron C, et al. ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice. Cell Death Differ. 2013 Aug;20(8):1017-30.)
- Monoclonal Antibody Pair raised by human Pro NGF Recombinant Protein
- Immunoreactivity with Human Pro NGF (19-121) and Pro NGF (19-241) at 100%
- Non-crossreactivity with human mature NGF (122-241)
- Monoclonal Antibody Pair specific to Pro-NGF (Human)
- Calibration by human Pro NGF (19-241)
- Size: 96 T
- Serum samples tested
Features
- Code No.: SK00307-06Size: 96TStandard range: 0.93-240 ng/mlSensitivity: 350 pg/mlSample Type: human serum, recombinant pro ngf, tissues homogenatesIntra-CV: 4-6%Inter-CV: 4-9%Data Sheet: PDF