Description
GP130/CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex.
- IL-6 Receptor subunit beta
- Interleukin 6 Signal Transducer (IL6ST)
- Glycoprotein 130
Feature:
- Monoclonal Antibody Pair specific to mouse IL6ST/GP130 (HEK293)
- Calibration by rm gp130 (HEK293)
- High Sensitivity at 5 pg/mL
- Samples Tested
- Size: 96T and 192T ($890 per 192 T)
References:
- Li Y, et al. gp130 Controls Cardiomyocyte Proliferation and Heart Regeneration. Circulation. 2020 Sep 8;142(10):967-982.
- Kawagishi H, et al. Cytokine receptor gp130 promotes postnatal proliferation of cardiomyocytes required for the normal functional development of the heart. Am J Physiol Heart Circ Physiol. 2022 Jul 1;323(1):H103-H120.
Features
Size: 96 T
Standard Range: 11.7-750 pg/ml
Sensitivity: 5 pg/ml
Sample Type: serum, EDTA plasma
Sample Requires: 100 ul per well of 200-300-fold diluted samples.
Intra-CV: 4-6%
Inter-CV: 4-9%