Uromodulin is a biomarker for Chronic Kidney Disease and Hypertension Research.
Protective role of uromodulin against urinary tract infection.
Uromodulin (also known as Tamm-Horsfall protein) is exclusively produced in the kidney and is the most abundant protein in normal urine. (Devuyst O, et al. Uromodulin: from physiology to rare and complex kidney disorders. Nat Rev Nephrol. 2017 Sep;13(9):525-544.)
Feature:
Calibaration by human urine Uromodulin Protein.
Antibody validated by WB and IP to human urine uromodulin.
Standard range: 1.56 ~ 400 ng/mL
Sensitivity: 0.3 ng/mL
Assay Specificity: Human
Sample Type: Urine (1:50 dilution), plasma, serum
Size:5 x 96 T.
Bulk Size available for inquires
New Research News:
Weiss GL, et al.. Architecture and function of human uromodulin filaments in urinary tract infections. Science. 2020 Aug 21;369(6506):1005-1010.
Alesutan I, et al.. Circulating uromodulin inhibits vascular calcification by interfering with pro-inflammatory cytokine signalling. Cardiovasc Res. 2021 Feb 22;117(3):930-941.