Description
Growth Differentiation Factor 15 Biomarker for Research
- Okada M, et al. Plasma growth differentiation factor 15: a novel tool to detect early changes of hereditary transthyretin amyloidosis. ESC Heart Fail. 2021 Apr;8(2):1178-1185
- Yang L, et al. GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand. Nat Med. 2017 Aug 28. doi: 10.1038/nm.4394.
- Kastritis E, et al. Growth differentiation factor-15 is a new biomarker for survival and renal outcomes in light chain amyloidosis. Blood. 2018 Apr 5;131(14):1568-1575
Citations:
Nandini Nair, and Enrique Gongora "Correlations of GDF-15 with sST2, MMPs, and worsening functional capacity in idiopathic dilated cardiomyopathy: Can we gain new insights into the pathophysiology?" J Circ Biomark. 2018 Jan 19;7:1849454417751735. doi: 10.1177/1849454417751735
Features
Size: 96 T
Standard Range: 6.25-400 pg/ml
Sensitivity: 2 pg/ml
Specificity: Human GDF15
Calibration: rh GDF15 Rec (HEK293)
Sample Type: serum, EDTA plasma
Sample Requires: 125 uL or less
Dilution Factor: 2~ 8
Intra-CV: 2-5%
Inter-CV: 4-8%
Protocol:
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