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High Sensitivity ELISA
Research Area
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ELISA
Recombinant
Antibody
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Neurotrophins
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Pro NGF (Human) ELISA Kit
Our Price:
$
690.00
Product Code:
SK00307-06
Qty:
Description
Technical Specs
More Information:
ProNGF, the precursor of mature nerve growth factor (NGF), is the most abundant form of NGF in the brain. ProNGF and mature NGF differ significantly in their receptor interaction properties and in their bioactivity. ProNGF increases markedly in the cortex of Alzheimer's disease (AD) brains and proNGF\NGF imbalance has been postulated to play a role in neurodegeneration. (Tiveron C, et al. ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice. Cell Death Differ. 2013 Aug;20(8):1017-30.)
Feature
:
Monoclonal Antibody Pair raised by human Pro NGF Recombinant Protein
Immunoreactivity with Human Pro NGF (19-121) and Pro NGF (19-241) at 100%
Non-crossreactivity with human mature NGF (122-241)
Monoclonal Antibody Pair specific to Pro-NGF (Human)
Calibration by human Pro NGF (19-241)
Size: 96 T
Serum samples tested
Features
Code No.: SK00307-06
Size: 96T
Standard range: 0.93-240 ng/ml
Sensitivity: 350 pg/ml
Sample Type: human serum, recombinant pro ngf, tissues homogenates
Intra-CV: 4-6%
Inter-CV: 4-9%
Data Sheet: PDF
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